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News
Company Announcements
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公司公告
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In November, Agilent Technologies signed a memorandum of understanding (MOU) with GI Innovation (GII), a Korean clinical-stage biopharmaceutical company. The MOU establishes a framework in which the two companies will enter into a strategic partnership to explore potential genomic biomarkers of the tumor microenvironment in an early-phase trial of the investigational compound GI-101. This is Agilent's first partnership of this kind in Korea. The Agilent NGS panel tumor profiling assay that will be used enables genomic profiling of more than 500 cancer-related genes in a single assay with measurement of tumor mutational burden (TMB) including microsatellite instability-high (MSI-H), as well as variants characterization in tumor suppressor genes and genes involved in homologous recombinant repair (HRR), important emerging biomarkers in immuno-oncology.
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11 月,安捷伦科技与韩国临床阶段的生物制药公司 GI Innovation(GII)签署了谅解备忘录(MOU)。谅解备忘录建立了一个框架,在该框架中,两家公司将建立战略合作伙伴关系,在研究化合物 GI-101 的早期试验中探索肿瘤微环境的潜在基因组生物标志物。这是安捷伦在韩国的首个此类合作伙伴关系。将要使用的安捷伦 NGS 平板肿瘤分析法可以在一次检测中对 500 多个癌症相关基因进行基因组分析,并测量肿瘤突变负荷(TMB),包括微卫星不稳定性高(MSI-H),以及肿瘤抑制基因和肿瘤抑制基因中的变体表征参与同源重组修复(HRR)的基因,是免疫肿瘤学中重要的新兴生物标志物。
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The Access to Comprehensive Genomic Profiling Coalition (ACGP) announced that seven diagnostics and lab service providers have joined: Exact Sciences, Foundation Medicine, Illumina, LabCorp, QIAGEN, Roche Diagnostics and Thermo Fisher Scientific. The goal of the organization is to collectively advocate for appropriate broad US health insurance coverage of comprehensive genomic profiling for patients living with advanced cancer.
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访问全面基因组分析联盟(ACGP)宣布,七家诊断和实验室服务提供商已加入:精确科学、基础医学、Illumina、LabCorp、QIAGEN、罗氏诊断和 Thermo Fisher Scientific。该组织的目标是共同倡导为晚期癌症患者提供适当的、广泛的美国健康保险覆盖范围,包括全面的基因组分析。
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In November, clinical genomics company PierianDx and executive search firm Bench International announced the appointment of Mark McDonough as CEO and a Board member. He most recently served as CEO and board member for Immunis.AI. He succeeds Chairman and Interim CEO Joe Boorady, who remains as Chairman.
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11 月,临床基因组学公司 PieriandX 和猎头公司 Bench International 宣布任命马克·麦克唐纳为首席执行官兼董事会成员。他最近担任 Immunis.AI 的首席执行官兼董事会成员。他继任董事长兼临时首席执行官乔·布拉迪,后者仍然担任董事长。
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PerianDx announced in December an expanded partnership with Illumina to enable PierianDx genomic reporting solutions for use with AmpliSeq for Illumina Focus Panel, AmpliSeq for Illumina Myeloid Panel and the TruSight Hereditary Cancer Panel.
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PeriandX 在 12 月宣布扩大与 Illumina 的合作伙伴关系,使 PieriandX 基因组报告解决方案能够与用于 Illumina Focus Panel 的 AmpliseQ、Illumina 髓系面板和 TrusSight 遗传性癌症小组的 AmpliseQ 配合使用。
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In December, Illumina announced that its NextSeq 550Dx NGS System received approval from China's National Medical Products Administration (NMPA) for genetic testing and diagnosis. The NextSeq 550Dx is Illumina's second clinical-grade sequencer to receive NMPA regulatory approval, following the 2018 approval of the MiSeq Dx. The NextSeq 550Dx has been cleared for IVDs in more than 40 countries.
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去年 12 月,Illumina 宣布其 NextSeq 550Dx NGS 系统获得了中国国家医疗产品管理局(NMPA)的批准,用于基因检测和诊断。NextSeq 550Dx 是继 MisEQ Dx 2018 年批准之后,Illumina 第二台获得 NMPA 监管机构批准的临床级测序器。NextSeq 550Dx 已在 40 多个国家/地区获准用于 IVD。
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In December, Illumina announced that Australia's Victorian Government collaborated with the University of Melbourne and Illumina to secure a $60 million investment for the Illumina–University of Melbourne Genomics Hub. The Hub combines Illumina's industry expertise with the support of the University of Melbourne's research and student body. According to Illumina, it is the first hub of its kind.
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去年 12 月,Illumina 宣布,澳大利亚维多利亚州政府与墨尔本大学和 Illumina 合作,为 Illumina — 墨尔本大学基因组学中心获得 6000 万美元的投资。该中心将 Illumina 的行业专业知识与墨尔本大学研究和学生团体的支持相结合。根据 Illumina 的说法,这是同类中的第一个枢纽。
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In December, Weill Cornell Medicine, NewYork-Presbyterian Hospital and Illumina announced a collaboration to sequence the complete human genomes of thousands of consenting patients in order to identify genetic alterations driving disease and potentially reveal previously unidentified therapies for treatment. The initiative, which also includes a collaboration between Weill Cornell Medicine, NewYork-Presbyterian Hospital and the New York Genome Center (NYGC), aims to evaluate the diagnostic potential of whole genome sequencing at scale. Under the initiative, which originates from Weill Cornell Medicine's Englander Institute for Precision Medicine, doctors at Weill Cornell Medicine and New York-Presbyterian/Weill Cornell Medical Center will offer qualifying patients the option to have their genomes sequenced as part of their diagnostic workups.
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去年 12 月,威尔康奈尔医学、纽约长老会医院和 Illumina 宣布合作,对成千上万同意的患者的完整人类基因组进行测序,以确定导致疾病的基因改变,并有可能揭示以前未知的治疗疗法。该计划还包括威尔康奈尔医学公司、纽约长老会医院和纽约基因组中心(NYGC)之间的合作,旨在大规模评估全基因组测序的诊断潜力。根据这项由威尔康奈尔医学的英格兰精准医学研究所提出的倡议,威尔康奈尔医学和纽约长老会/威尔康奈尔医学中心的医生将为符合条件的患者提供将其基因组测序作为诊断的一部分的选项检查。
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Illumina and Harvard Pilgrim Health Care announced in December a risk sharing agreement to make whole genome sequencing (WGS) available to certain Harvard Pilgrim members, effective January 1, 2021. The program will leverage WGS to support faster diagnoses of genetic diseases in children. Through this agreement, Harvard Pilgrim and Illumina will work together to evaluate how insurance coverage of WGS impacts patient care and healthcare costs. During the term of the agreement, Harvard Pilgrim will cover WGS through their network of lab providers for pediatric patients meeting specific criteria. Illumina and Harvard Pilgrim will share the risk on genetic testing costs.
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Illumina 和 Harvard Pilgrim Health Care 于 12 月宣布了一项风险分担协议,将全基因组测序(WGS)提供给某些哈佛朝圣者成员,自 2021 年 1 月 1 日起生效。该计划将利用 WGS 支持更快地诊断儿童的遗传疾病。通过这项协议,哈佛朝圣者和 Illumina 将共同评估 WGS 的保险范围如何影响患者护理和医疗保健成本。在协议期内,哈佛朝圣者将通过其实验室提供商网络为符合特定标准的儿科患者提供 WGS 服务。Illumina 和哈佛朝圣者将分担基因检测成本的风险。
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TwinStrand Biosciences announced in November it entered into agreement to sublicense two foundational patent families to molecular information company Foundation Medicine and its affiliates relating to TwinStrand Duplex Sequencing error-correction technology. Duplex Sequencing increases the accuracy of NGS as much as 10,000 times, according to the company, allowing the detection of ultra-low frequency mutations.
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TwinS朗生物科学公司于 11 月宣布,它已签署协议,向分子信息公司 Foundation Medicine 及其关联公司转授两个基础专利家族,这些专利家族与 TwinScan Duplex 测序纠错技术有关。该公司称,双工测序可将 NGS 的准确性提高多达 10,000 倍,从而可以检测到超低频突变。
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Omniome, a developer of a novel DNA sequencing platform, appointed Robert Wicke as CEO in November. He served most previously as CEO of Halo Labs.
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新型 DNA 测序平台的开发者 Omniome 于 11 月任命罗伯特·威克为首席执行官。他以前担任 Halo Labs 的首席执行官。
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Third quarter revenues for HTG Molecular Diagnostics, a life science company whose mission is to advance precision medicine fell 67.1% to $1.8 million (see Bottom Line). Product and product-related services sales declined 60.5% to $1.7 million, while Collaborative development services revenue was down 93.0% to $0.76 million. The company ended the quarter with $30.5 million in cash, cash equivalents and short-term available-for-sale securities.
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生命科学公司 HTG 分子诊断公司的第三季度收入下降了 67.1%,至 180 万美元(见底线)。产品和产品相关服务的销售额下降了 60.5%,至 170 万美元,而协作开发服务收入下降了 93.0%,至 76 万美元。该公司在本季度末获得了 3,050 万美元的现金、现金等价物和短期可供出售证券。
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In November, HTG Molecular Diagnostics announced that as a result of its 1-for-15 reverse stock split, its common stock will begin trading on a split-adjusted basis on the Nasdaq effective November 23. Holders received a cash payment in lieu of fractional shares.
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11 月,HTG 分子诊断公司宣布,由于其 1 比 15 的反向股票拆分,其普通股将于 11 月 23 日开始在纳斯达克按拆分调整后的基础上交易。持有人收到现金支付代替部分股份。
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According to a November report on Nordic9, Single Technologies, developer of the Theta 3D sequencing platform, raised $6.1 million, adding to the $3 million previously raised. The platform utilizes confocal scanning and nanofluidic technology to combine NGS and spatial genomics.
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根据 11 月有关 Nordic9 的报告,Theta 3D 测序平台的开发商 Single Technologies 筹集了 610 万美元,与之前筹集的 300 万美元相比增加了此前筹集的 300 万美元。该平台利用共聚焦扫描和纳米流体技术将 NGS 和空间基因组学相结合。
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OHMX.bio, a provider of omics solutions, and IVD testing firm Fujirebio Europe were awarded a €720,000 ($872,771) research grant from Flanders Innovation & Entrepreneurship (VLAIO) to develop a clinical IVD platform incorporating third-generation sequencing technologies. The IVD-seq project will initially focus on a cost efficient, accurate and portable IVD modular solution for highly polymorphic regions.
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组学解决方案提供商 Ohmx.bio 和 IVD 测试公司 Fujirebio Europe 获得了法兰德斯创新与企业家精神(VLAIO)提供的 72 万欧元(合 872,771 美元)的研究资助,用于开发结合第三代测序技术的临床 IVD 平台。IVD-Seq 项目最初将专注于针对高度多态区域的经济高效、准确和便携式的 IVD 模块化解决方案。
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Product Introductions
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产品介绍
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Twist Bioscience, a company offering high-quality synthetic DNA using its silicon platform, announced in November the availability of the Twist Comprehensive Viral Research Panel, an NGS panel that includes more than 3,000 viral genomes. The panel is bundled with an analysis platform from OneCodex to enable an end-to-end workflow.
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Twist Bioscience 是一家利用其硅平台提供高质量合成 DNA 的公司,该公司于 11 月宣布推出 Twist 综合病毒研究小组,该小组包括 3,000 多个病毒基因组。该面板与 OneCoDEX 的分析平台捆绑在一起,以实现端到端的工作流程。
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In November, Twist Bioscience and Biotia, a company that uses analytical software for infectious disease diagnostics, made available the RUO SARS-CoV-2 NGS Assay. The Assay is a highly sensitive nucleic acid hybridization capture–based assay used for detection, characterization and environmental monitoring of the SARS-CoV-2 virus. The test spans both diagnostic methods and vaccine research.
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11 月,Twist Bioscience 和使用分析软件进行传染病诊断的 Biotia 公司推出了 RUO SARS-CoV-2 NGS 检测。该检测方法是一种基于高灵敏度核酸杂交捕获的检测方法,用于 SARS-CoV-2 病毒的检测、表征和环境监测。该测试涵盖诊断方法和疫苗研究。
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Oxford Nanopore released in November the MinKNOW App for iOS and Android devices. MinKNOW is the operating software that drives nanopore sequencing devices. It carries out several core tasks, including data acquisition, real-time analysis and feedback, local base calling and data streaming, while providing device control including selecting the run parameters, sample identification and tracking, and ensuring that the platform chemistry is performing correctly.
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牛津纳米波尔在 11 月发布了适用于 iOS 和 Android 设备的 MinNnow 应用程序。minNnow 是驱动纳米孔测序设备的操作软件。它执行多项核心任务,包括数据采集、实时分析和反馈、本地基本呼叫和数据流,同时提供设备控制,包括选择运行参数、样品识别和跟踪,以及确保平台化学运行正确。
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In December, Oxford Nanopore announced several new releases, including improvements in its PromethION flow cells that have enabled a new 10 Terabase sequencing record, modal single-read accuracy of 99.1% using a new sequencing chemistry currently in development, high-accuracy variant calling tools and automation options for nanopore sequencing experiments at any scale. In November, Oxford Nanopore started to ship PromethION flow cells that incorporate a number of iterative improvements in yields and consistency. These improvements have culminated in a 10 Tb internal run using all 48 Flow Cells, a 25% improvement over the previous record.
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去年 12 月,牛津纳米波尔宣布了几个新版本,包括改进了 ProMethion 流通池,创造了新的 10 Terabase 测序记录,使用目前正在开发的新测序化学物质的模态单读精度达到 99.1%,高精度变体调用工具和自动化任何规模的纳米孔测序实验的选项。11 月,牛津纳米波尔开始出货 ProMethion 流通池,该流通池在产量和一致性方面进行了多次迭代改进。这些改进最终导致使用所有 48 个流通池的 10 Tb 内部运行,比之前的记录提高了 25%。
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HTG Molecular Diagnostics launched in December an Early Access Program for its whole transcriptome panel using the HTG EdgeSeq technology. It features the ability to run small sample sizes without requiring RNA isolation and purification and the ability to successfully process low-quality samples.
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HTG 分子诊断公司于 12 月启动了使用 HTG EdgSeq 技术的整个转录组面板的抢先体验计划。它具有在不需要 RNA 分离和纯化的情况下运行小样本的能力,并且能够成功处理低质量的样本。
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Sales and Orders of Note
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销售和注意订单
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In December, Agilent Technologies announced its clinical informatics platform Alissa Interpret was adopted by the North West Genomic Laboratory Hub (NW GLH) based in Manchester and Liverpool, part of Manchester University NHS Foundation Trust, England. The NW GLH and its partners are responsible for delivering genomic testing across the whole of the North West. Alissa Interpret, which enables clinical genetics labs to standardize and automate variant triage, review, classification and reports on NGS data, becomes 1 of 2 platforms the NW GLH will use to analyze genomics data.
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12 月,安捷伦科技宣布其临床信息学平台 Alissa Trust 被位于曼彻斯特和利物浦的西北基因组实验室中心(NW GLH)采用,该中心隶属于英国曼彻斯特大学 NHS 基金会信托基金会。西北 GLH 及其合作伙伴负责在整个西北地区提供基因组测试。Alissa Deromate 使临床遗传学实验室能够对 NGS 数据的变异分类、审查、分类和报告进行标准化和自动化,成为西北 GLH 将用于分析基因组学数据的 2 个平台之一。
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Pacific Biosciences of California, a provider of high-quality sequencing of genomes, transcriptomes and epigenomes, announced in December that the UK's Edinburgh Genomics, Oxford Genomics Center and University of Liverpool Centre for Genomic Research each added Sequel II or Sequel IIe Systems to expand the delivery of highly accurate long-read sequencing services.
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提供高质量基因组、转录组和表观基因组测序的提供商加利福尼亚太平洋生物科学公司于 12 月宣布,英国的爱丁堡基因组学、牛津基因组学中心和利物浦大学基因组研究中心各增加了续集 II 或 Sequence IIe扩大提供高精度长读测序服务的系统。
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MS & LC/MS
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Translation in progress...
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Company Announcements
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公司公告
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In November, Megadalton Solutions, an early-stage biotech with expertise in large-molecule analysis by Charge Detection Mass Spectrometry (CDMS), announced the expansion of a collaboration with Waters to bring CDMS technology to a broader set of applications and potential customers in biopharma. The CDMS detector provides a high-throughput analytical tool for the cell and gene therapy sectors. Waters became a strategic investor in the firm in 2020.
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11 月,拥有电荷检测质谱(CDMS)大分子分析专业知识的早期生物技术公司 Megadalton Solutions 宣布扩大与沃特世的合作,将 CDMS 技术推向生物制药领域更广泛的应用和潜在客户。CDMS 检测器为细胞和基因治疗领域提供了高通量的分析工具。沃特世于 2020 年成为该公司的战略投资者。
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In December, Waters formally expanded its long standing collaborative relationship with Dr. Sunghwan Kim of South Korea's Kyungpook National University to further explore the use of Waters' ion mobility spectrometry (IMS) in the investigation of compounds in complex mixtures, such as oil. In addition, they will work to characterize complex advanced materials used in high-technology products, such as those found in electronics.
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去年 12 月,沃特世正式扩大了与韩国庆北国立大学的 Sunghwan Kim 博士的长期合作关系,以进一步探讨如何使用沃特世的离子迁移谱法(IMS)研究复杂混合物(例如油)中的化合物。此外,他们还将致力于表征高科技产品中使用的复杂先进材料,例如电子产品中的那些材料。
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Lipidomics Consulting, together with scientists at the University of Wollongong (UoW), Maastricht MultiModal Molecular Imaging Institute (M4I), MOBILion Systems and Merck & Co., announced in November that they have received a grant from the Michael J. Fox Foundation for Parkinson's Research (MJFF) and its partner, the Shake It Up Australia Foundation. The group will work to identify alterations in the metabolism of selective glycosphingolipids in specific brain regions that contribute to early Parkinson's onset and accelerated progression rates. MOBILion Systems' high-resolution ion mobility (SLIM) technology will provide glycosphingolipid measurements.
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Lipidomics Consulting 与卧龙岗大学(UoW)、马斯特里赫特多模态分子影像研究所(M4I)、Mobilion Systems 和默克公司的科学家一起宣布,他们已获得迈克尔 ·J· 福克斯帕金森研究基金会(MJFF)及其合伙人,Shake It Up 澳大利亚基金会。该小组将致力于确定特定大脑区域中选择性糖皮脂代谢的变化,这些变化有助于帕金森早期发病和加速进展速度。Mobilion Systems 的高分辨率离子迁移率 (SLIM) 技术将提供糖皮脂测量。
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In November, JEOL USA, a supplier of mass spectrometers, electron microscopes, and NMR spectrometers, announced that it began collaborating with Think20 Labs to provide improved and more precise analytical techniques to the cannabis testing market. Think20 Labs is a start-up company based in California that is licensed by the California Bureau of Cannabis Control to test cannabis, hemp and cannabis-related consumer products for regulatory requirements. The strategic partnership aims to develop cannabis-specific methods for the analysis of trace pesticides and terpenes in cannabis products based on the capabilities of JOEL's TQ-4000 MS system.
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11 月,质谱仪、电子显微镜和核磁共振光谱仪的供应商 JEOL USA 宣布开始与 Think20 Labs 合作,为大麻测试市场提供改进,更精确的分析技术。Think20 Labs 是一家位于加利福尼亚的初创公司,获得了加利福尼亚大麻管制局的许可,可以根据监管要求测试大麻,大麻和与大麻相关的消费品。该战略伙伴关系旨在根据 JOEL 的 TQ-4000 MS 系统的功能,开发针对大麻的方法,用于分析大麻产品中的痕量农药和萜烯。
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In November, Banner Industries, a flow component distributor for high-purity and industrial manufacturing, announced a partnership with Atonarp, effective October 15 for application in fields such as semiconductors. Atonarp's miniature MS products cater to processes that require advanced molecular analysis for a variety of markets, including pharmaceutical, semiconductor, industrial and biological applications.
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11 月,面向高纯度和工业制造的流体组件分销商 Banner Industries 宣布与 Aronarp 建立合作伙伴关系,该合作伙伴关系将于 10 月 15 日生效,在半导体等领域的应用。Aronarp 的微型 MS 产品可满足各种市场需要高级分子分析的工艺,包括制药、半导体、工业和生物应用。
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In December, Newomics, a biotech company developing and commercializing MS solutions for molecular detection applications, announced the closing of a $7.9 million Series B financing, led by MSA Capital. Joining the round were new investor LDV Partners, and existing Series A investors, including the Berkeley Catalyst Fund and the Photon Fund.
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去年 12 月,一家开发和商业化用于分子检测应用的 MS 解决方案的生物技术公司 Newomics 宣布完成由 MSA Capital 领导的 790 万美元的 B 轮融资。新投资者 LDV Partners 以及包括伯克利催化剂基金和光子基金在内的现有 A 轮投资者加入了这一轮。
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Product Introductions
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产品介绍
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In November, Shimadzu Scientific Instruments launched the RUO Amyloid Mass Spectrometry Service for early screening of amyloid-positive subjects in the US. This simple blood analysis method enables early and accurate prediction of amyloid pathology in the brain, according to the company. The blood analysis works using a combination of immunoprecipitation and MALDI-TOF MS (IP-MS)
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11 月,岛津科学仪器推出了 RUO 淀粉样蛋白质谱服务,用于在美国对淀粉样蛋白阳性受试者进行早期筛查。该公司称,这种简单的血液分析方法可以及早准确地预测大脑中的淀粉样蛋白病理学。血液分析结合免疫沉淀和 MALDI-TOFMS(IP-MS)进行
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Company Announcements
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公司公告
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In November, Agilent Technologies announced that a collaboration with SGS resulted in a new GC/TQ method, the SGS AXYS Method 16130, approved by the US EPA as an alternative method for the future regulation and detection of dioxin. The previous US EPA dioxin testing method, EPA 1613B, required the use of magnetic sector instruments.
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11 月,安捷伦科技宣布,通过与 SGS 的合作,推出了一种新的 GC/TQ 方法,即 SGS AXYS 方法 16130,该方法已获得美国环保局的批准,作为未来监管和检测二恶英的替代方法。之前的美国环保局二恶英测试方法 EPA 1613B 要求使用磁性部门仪器。
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Third quarter sales for Repligen, which develops and commercializes bioprocessing technologies and systems, grew 35.4% to $94.1 million, including 31% organic growth, with COVID-related revenues accounting for approximately 14% of total sales. Non-COVID organic sales grew 17%, including more than 30% growth related to gene therapy. By product line, process analytical sales rose approximately 30%, protein sales were up close to 20% and filtration demand grew over 50%.
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开发和商业化生物加工技术和系统的 Repligen 的第三季度销售额增长了 35.4%,至 9,410 万美元,包括 31% 的有机增长,与 COVID 相关的收入约占总销售额的 14%。非 COVID 有机销售额增长了 17%,其中包括与基因疗法相关的 30% 以上的增长。按产品线划分,过程分析销售额增长约 30%,蛋白质销售额增长接近 20%,过滤需求增长了 50% 以上。
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Repligen raised its full-year revenue forecast to $348–$352 million and overall revenue growth to 29%–30%, including 23%–24% organic growth, up from July's estimate of 18%–21% growth. COVID-related sales are expected to represent 10% of 2020 revenues. For the year, on an organic basis, Repligen expects filtration sales to be up 35%, 15%–20% growth from the OPUS product line, 25%–30% pro forma growth for process analytics, and protein sales to grow 15%–20%.
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Repligen 将其全年收入预测提高至 3.48 亿至 3.52 亿美元,整体收入增长至 29% 至 30%,包括 23% 至 24% 的自然增长,高于 7 月份的 18% 至 21% 的增长率。预计与 COVID 相关的销售额将占 2020 年收入的 10%。在有机基础上,Repligen 预计今年的过滤销售额将比 OPUS 产品线增长 35%,15% 至 20%,过程分析的预计增长 25% 至 30%,蛋白质销售将增长 15% 至 20%。
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In December, Repligen announced the closing of an underwritten public offering of an aggregate of 1.725 million shares of its common stock at a public offering price of $181 per share. The offering of the shares is expected to result in approximately $298 million in net proceeds to Repligen after deducting underwriting discounts and commissions and other estimated offering expenses payable by Repligen.
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去年 12 月,Repligen 宣布以每股 181 美元的公开发行价结束其普通股的承销公开发行,其普通股总额为 172.5 万股。在扣除承销折扣和佣金以及 Repligen 应支付的其他预计发售费用后,预计将为 Repligen 带来约 2.98 亿美元的净收益。
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In November, Alpha MOS named John Morris Group as a distributor for Australia and New Zealand.
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11 月,Alpha MOS 任命约翰·莫里斯集团为澳大利亚和新西兰的分销商。
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In December, Bormioli Pharma acquired ISO Arzneiverpackungen, a German company specializing in the production of pharmaceutical packaging, including tubular glass vials designed for the injectable drugs and chromatography vials.
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去年 12 月,Bormioli Pharma 收购了 ISO Arzneiverpackungen,这是一家专门生产药品包装的德国公司,包括为注射药物设计的管状玻璃瓶和色谱瓶。
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In December, Global Allied Processing Solutions (G-APS) announced its strategic focus on the global organic material industry. Founding members RotaChrom Technologies, the developer of an industrial-scale centrifugal partition chromatography technology platform, and Heidolph Instruments, a provider of premium laboratory equipment, created G-APS to further establish best practices for the processing of raw materials. G-APS' goal is to provide businesses with one-stop-shop access to multiple solutions for their processing and manufacturing infrastructure needs, with a specific focus on the extraction and purification of botanically derived compounds and molecules.
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去年 12 月,全球联合加工解决方案公司(G-APS)宣布了其对全球有机材料行业的战略重点。创始成员 RotachROM Technologies 是工业规模的离心分区色谱技术平台的开发商,以及优质实验室设备供应商海道夫仪器公司创建了 G-APS,以进一步建立原材料加工的最佳实践。G-APS 的目标是为企业提供一站式服务,以满足其加工和制造基础设施需求的多种解决方案,特别关注植物衍生化合物和分子的提取和纯化。
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Product Introductions
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产品介绍
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In November, Shimadzu launched the Advanced i-Series HPLC, encompassing the LC-2050 and LC-2060. Compared to the i-Series, the Advanced i-Series boasts increased pressure resistance and additional functions to support remote work including working from home. Since its release in 2014, the original i-Series HPLC has achieved sales of over 20,000 units.
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11 月,岛津推出了先进的 i 系列 HPLC,包括 LC-2050 和 LC-2060。与 I 系列相比,Advanced I 系列具有更高的耐压性和支持远程办公的附加功能,包括在家办公。自 2014 年发布以来,最初的 i 系列 HPLC 已实现了超过 2 万台的销量。
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Shimadzu Scientific Instruments debuted in November the ELSD-LT III evaporative light scattering detector. It uses a high-power semiconductor laser as the light source, which enables sensitivity approximately 10 times higher than that of conventional products, the highest level of sensitivity for an ELSD, according to the company. The ELSD-LT III achieves a wide dynamic range of 5 orders of magnitude, providing simultaneous determination of high-concentration and trace components without gain switching.
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岛津科学仪器于 11 月首次亮相 ELSD-LT III 蒸发光散射探测器。据该公司称,它使用高功率半导体激光器作为光源,其灵敏度比传统产品高约 10 倍,是 ELSD 的最高灵敏度水平。ELSD-LT III 可实现 5 个数量级的宽动态范围,无需增益切换即可同时测定高浓度和痕量成分。
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PerkinElmer launched in November the LC 300 platform and SimplicityChrom software, bringing together advanced HPLC and UHPLC capabilities with intuitive instrument control and data analysis for the food, cannabis, pharmaceutical and chemical arenas. The versatile platform features multiple detector options and third-party driver support for commercially available CDS systems.
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PerkinElmer 于 11 月推出了 LC 300 平台和 SimplicityChrom 软件,将先进的 HPLC 和 UHPLC 功能与食品、大麻、制药和化学领域的直观仪器控制和数据分析结合在一起。该多功能平台具有多种探测器选项,并支持市售 CDS 系统的第三方驱动程序。
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In November, Alfa Chemistry, a supplier of analytical chemistry reagents, announced the release of a variety of chromatography standards, mainly for the purpose of calibration.
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11 月,分析化学试剂供应商阿尔法化学宣布发布各种色谱标准,主要用于校准目的。
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Activated Research Company (ARC) unveiled in November a stop-flow modulation solution for comprehensive GCxGC, allowing it to be an attainable configuration for any analytical laboratory, according to the firm. ARC's solution takes advantage of stop-flow modulation and allows for low cost implementation; simple, easy installation; increased peak capacity through comprehensive analyte transfer; unattended or remote operation; streamlined operation through dedicated software; and straightforward switching between 1D and 2D GC.
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该公司表示,Activated Research Company(ARC)于 11 月推出了用于综合 GCxGC 的停流调制解决方案,这使其成为任何分析实验室都可以实现的配置。ARC 的解决方案利用停流调制,实现低成本;安装简单易行;通过全面的分析物转移提高峰容量;无人值守或远程操作;通过专用软件简化操作;以及在一维之间直接切换和 2D GC。
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In December, Orange Photonics launched the LightLab 3 Cannabis Analyzer Law Enforcement Version, specifically designed to support rapid presumptive and quantitative cannabis analysis by non-technical personnel in a non-laboratory setting. LightLab 3 Cannabis Analyzer, compliant with US Department of Agriculture hemp testing technology requirements, is the only portable HPLC on the market, according to the firm. In quantitative mode, it measures up to 11 cannabinoids including D9THC and CBD, with a limit of detection of 0.5%–0.05% depending on sample type.
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12 月,Orange Photonics 推出了 LightLab 3 大麻分析仪执法版本,该版本专为支持非技术人员在非实验室环境中进行快速推定和定量的大麻分析而设计。该公司称,符合美国农业部大麻测试技术要求的 LightLab 3 大麻分析仪是市场上唯一的便携式 HPLC。在定量模式下,它可以测量多达 11 种大麻素,包括 D9THC 和 CBD,根据样本类型的不同,检出限为 0.5% — 0.05%。
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Sales and Orders of Note
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销售和注意订单
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AgraFlora Organics announced in November that it added an Agilent Technologies HPLC for its 51,000 ft2 (4,738 m2) automated edibles manufacturing facility in Winnipeg, Canada.
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AgraFlora Organics 在 11 月宣布,它为其位于加拿大温尼伯的 51,000 平方英尺(4,738 平方米)的自动化零嘴制造工厂增加了安捷伦科技 HPLC。
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Purolite, a manufacturer of resin-based separation, purification and extraction technologies, announced it will supply its Protein A capture resin, Praesto Jetted A50 to WuXi Biologics. WuXiBiologics, a global company with leading open-access biologics technology, will utilize Praesto Jetted A50 to provide its customers with additional choices for affinity chromatography resins for a range of downstream processes for mAb purification. The Praesto line of agarose-based chromatography resins are currently utilized in over 200 screening projects and ongoing clinical trials.
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树脂基分离、纯化和提取技术制造商 Purolite 宣布将向无锡生物制药供应其蛋白 A 捕获树脂 Praesto Jetted A50。WuxiBioLogics 是一家拥有领先开放获取生物制剂技术的全球性公司,将利用 Praesto Jetted A50 为客户提供更多的亲和色谱树脂选择,用于单克隆抗体纯化的一系列下游工艺。基于琼脂糖的色谱树脂 Praesto 系列目前已用于 200 多个筛选项目和正在进行的临床试验。
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Cape Business News reported in November that WearCheck, a condition monitoring lab, purchased four new chromatography systems from PerkinElmer for its transformer division labs in Johannesburg, Durban and Cape Town, South Africa.
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开普商业新闻 11 月报道说,状态监测实验室 WearCheck 从 PerkinElmer 购买了四套新的色谱系统,用于其在南非约翰内斯堡、德班和开普敦的变压器部门实验室。
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Company Announcements
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公司公告
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Gemini Bioproducts, a supplier of cell culture solutions and a portfolio company of Bel Health Investment Partners, announced in August a US distribution agreement with Scinus Cell Expansion Netherlands for the Scinus Cell expansion bioreactor system.
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Gemini Bioducts 是细胞培养解决方案的供应商,也是 Bel Health Investment Partners 的投资组合公司,该公司于 8 月宣布了与荷兰 Scanus Cell 扩张系统的美国分销协议,用于 Scanus Cell 膨胀生物反应器系统。
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In October, life sciences firm Cytiva announced it plans to open its new 80,000 ft2 (7,432 m2) manufacturing facility in Shrewsbury, Massachusetts, by the end the year as part of its five-year, $500 million investment to expand its global manufacturing capacity. The facility will significantly increase Cytiva's capacity to manufacture Xcellerex Bioreactors and will free up capacity in its Westborough facility to manufacture complementary single-use technologies. The new facility will have five manufacturing lines operating 24/7, a new clean room and an R&D lab.
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10 月,生命科学公司 Cytiva 宣布,计划在今年年底之前在马萨诸塞州什鲁斯伯里开设新的 8 万平方英尺(7,432 平方米)的制造工厂,作为其五年 5 亿美元投资的一部分,用于扩大其全球制造能力。该工厂将大大提高 Cytiva 生产 Xcellerex 生物反应器的能力,并将释放其韦斯特伯勒工厂的生产能力,用于制造互补的一次性技术。新工厂将有五条全天候运营的生产线,一个新的洁净室和一个研发实验室。
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In November, Cytiva announced deals pledging to invest in fields of manufacturing, bioprocess development and research to accelerate the development and manufacture of therapeutics and benefit patients in China and beyond. Cytiva and manufacturer Wego announced plans to triple single-use manufacturing capacity in Asia Pacific to produce bags, components and other customized products. A comprehensive strategic partnership with vaccine producer Zhifei allows the pair to work on process development, raw material supply, service and personnel training. Under the upgraded partnership with Clover Biopharmaceuticals, Cytiva will help the global clinical-stage biotech company add two more 2000 L bioreactors for a total of 4 x 2000 L manufacturing capacity through the Cytiva FlexFactory (see below). Cytiva also committed to creating a "Joint Lab on Human Collagen New Material" with pharmaceutical company Jinbo.
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11 月,Cytiva 宣布了一些协议,承诺在制造、生物工艺开发和研究领域进行投资,以加快治疗药物的开发和制造,使中国及其他地区的患者受益。Cytiva 和制造商 Wego 宣布计划将亚太地区的一次性生产能力提高三倍,以生产袋子、组件和其他定制产品。与疫苗生产商智飞的全面战略合作伙伴关系使他们能够在工艺开发、原材料供应、服务和人员培训方面开展工作。根据与三叶草生物制药公司的升级合作伙伴关系,Cytiva 将通过 Cytiva FlexFactory 帮助这家全球临床阶段的生物技术公司再增加两台 2000 升生物反应器,总制造能力为 4 x 2000 升(见下文)。Cytiva 还承诺与制药公司 Jinbo 共同创建 “人类胶原蛋白新材料联合实验室”。
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Cytiva expanded its offering at its Fast Trak research and training facilities in December in South Korea, Japan, Cambridge, UK, and Uppsala, Sweden. The expanded offering will support the growing cell and gene therapy industry, complementing current services provided in Shanghai, Toronto, and Marlborough, Massachusetts. Process development, media and assay development, and contract development services for preclinical through Phase 1 manufacturing will now be offered at all locations.
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Cytiva 于 12 月扩大了在韩国、日本、英国剑桥和瑞典乌普萨拉的 Fast Trak 研究和培训机构的产品范围。扩大的产品将支持不断发展的细胞和基因治疗行业,补充目前在上海、多伦多和马萨诸塞州马尔堡提供的服务。现在,所有地点都将提供临床前至第一阶段制造的工艺开发、培养基和检测开发以及合同开发服务。
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Erbi Biosystems, a microfluidic bioprocess instrumentation company, announced in October that it closed a finance round which brings the total investment received to nearly $4 million. The round was led by Jaguar Biotech. The funding will be used to expand manufacturing, sales and support of the 2 mL TruePerfusion Breez bioreactor and also to support further technology and product development. Erbi's technology will expand to cover all scaled down unit operations in bioprocessing.
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微流控生物过程仪器公司 Erbi Biosystems 于 10 月宣布完成了一轮融资,使收到的总投资达到近 400 万美元。本轮比赛由捷豹生物技术领导。这笔资金将用于扩大 2 mL TrueperFusion Breez 生物反应器的制造、销售和支持,还将用于支持进一步的技术和产品开发。Erbi 的技术将扩展到涵盖生物加工中所有缩小规模的单位操作。
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In November, MilliporeSigma and biotherapeutics company Transcenta, announced a strategic technology collaboration to implement continuous manufacturing for protein therapeutics. The unique model of collaboration brings the teams together in real time to converge single-use, continuous and digital bioprocessing technologies for the further development of Transcenta's integrated continuous bioprocessing (ICB) platform. As part of the initiative, MilliporeSigma and Transcenta will co-develop a first-of-its-kind, single-use flow-through polishing system. This highly collaborative relationship leverages MilliporeSigma's BioContinuum Platform.
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11 月,MilliporesIGMA 和生物治疗公司 Transcenta 宣布了一项战略技术合作,以实施蛋白质疗法的连续生产。独特的协作模式将团队实时聚集在一起,融合一次性使用、连续和数字生物处理技术,以进一步开发 Transcenta 的集成连续生物处理(ICB)平台。作为该计划的一部分,Milliporesigma 和 Transcenta 将共同开发同类首款一次性直通抛光系统。这种高度协作的关系充分利用了 MilliporesIGMA 的 BioContinum 平台。
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MilliporeSigma announced in December the broadening of its manufacturing footprint in Massachusetts. One expansion will add 65,000 ft2 (6,039 m2) of space to its Danvers single-use assembly operations, adding to the existing 120,000 ft2 (11,148 m2) facility. The expansion will add the capacity across several portfolios, including MilliporeSigma's Mobius single-use consumables. The total investment in Danvers is about $25 million and will add approximately 400 jobs throughout 2021. Jaffrey expansion plans include adding 25,000 ft2 (2,323 m2) to the existing 260,000 ft2 (24,155 m2) facility. The additional capacity will support filtration devices and membrane products, specifically Durapore filters, Express filters and the Viresolve product lines. The total investment in Jaffrey is about $22 million and is expected to bring nearly 275 roles by 2022, once completed.
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MilliporesIGMA 于 12 月宣布扩大其在马萨诸塞州的制造业足迹。一次扩建将为其丹佛斯一次性装配业务增加 65,000 平方英尺(6,039 平方米)的空间,增加现有的 12 万平方英尺(11,148 平方米)的设施。此次扩张将增加多个产品组合的产能,包括 MilliporesIGMA 的 Mobius 一次性耗材。对丹佛斯的总投资约为 2500 万美元,将在 2021 年全年增加约 400 个工作岗位。贾弗里的扩建计划包括在现有的 26 万平方英尺(24,155 平方米)的设施中增加 25,000 平方英尺(2,323 平方米)的设施。额外的容量将支持过滤设备和膜产品,特别是 Durapore 过滤器、Express 过滤器和 Viresolve 产品线。Jaffrey 的总投资约为 2,200 万美元,一旦完成,预计到 2022 年将增加近 275 个职位。
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In December, RoosterBio, a supplier of cellular therapy bioprocess tools and scalable manufacturing solutions for regenerative medicine, entered into an exclusive agency agreement with Sartorius Korea Biotech for its advanced platform of RUO and cGMP-grade hMSC working cell banks, optimized paired media and hMSC bioprocess systems.
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去年 12 月,再生医学细胞疗法生物工具和可扩展制造解决方案的供应商 RoosterBio 与赛多利斯韩国生物技术公司签订了独家代理协议,用于其先进的 RUO 和 cGMP 级 hmSC 工作细胞库、优化的配对介质和 hMSC生物过程系统。
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In December, CRO Evotec and Sartorius entered into a partnership with Curexsys, a German firm specializing in therapeutic exosomes. Curexsys delivers an isolation technology for exosomes based on a traceless immune-affinity process. Evotec and Curexsys will collaborate with the production of hMSCs, which serve as a source for exosomes. Evotec and Sartorius have formed a consortium to jointly invest in Curexsys' €8.2 million ($9.9 million) seed financing round with Evotec acquiring an equity stake of approximately 37% and Sartorius acquiring an approximately 21% stake. The partnership combines Evotec's industrial-grade iPSC and PanOmics platforms with Curexsys' exosome isolation technology and Sartorius' ability to translate these into a fully GMP-compliant process.
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去年 12 月,CRO Evotec 和赛多利斯与专门从事治疗性外泌体的德国公司 Curexsys 建立了合作伙伴关系。Curexsys 基于无痕免疫亲和过程为外泌体提供了一种隔离技术。Evotec 和 Curexsys 将与 HMSC 的生产合作,后者是外泌体的来源。Evotec 和赛多利斯组成了一个财团,共同投资库雷克瑟斯 820 万欧元(合 990 万美元)的种子融资,Evotec 收购了约 37% 的股权,赛多利斯收购了约 21% 的股份。该合作伙伴关系将 Evotec 的工业级 iPSC 和 Panomics 平台与 Curexsys 的外泌体隔离技术以及赛多利斯将其转化为完全符合 GMP 要求的工艺的能力相结合。
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Sales and Orders of Note
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销售和注意订单
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ABEC, a provider of integrated solutions and services for biopharmaceutical manufacturing, announced in October it is delivering process systems to CDMO Ology Bioservices (Ology Bio) to support their production of critical vaccines and therapeutics for COVID-19. ABEC is providing these systems to Ology Bioservices' Medical Countermeasures Advanced Development and Manufacturing (MCM ADM) facility in Alachua, Florida.
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生物制药制造集成解决方案和服务提供商 ABEC 于 10 月宣布,将向 CDMO Oology Bioservices(Oology Bio)交付工艺系统,以支持其生产 COVID-19 的关键疫苗和疗法。ABEC 正在向位于佛罗里达州阿拉楚阿的 Oology Bioservices 的医疗对策高级开发和制造(MCM ADM)工厂提供这些系统。
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In October, ABEC announced it will be providing CSR single-use mammalian cell culture and microbial fermentation systems, including the industry's first 6,000 L single-use bioreactor, to BioInno Bioscience's new contract development and manufacturing facility in Suzhou, Jiangsu, China. The facility is expected to be operational by mid-2021.
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10 月,ABEC 宣布将向 BioInno Bioscience 在中国江苏苏州的新合同开发和制造工厂提供 CSR 一次性哺乳动物细胞培养和微生物发酵系统,包括业界首台 6000 升一次性生物反应器。该设施预计将于 2021 年年中投入运营。
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In November, ABEC announced that New England Biolabs (NEB) selected ABEC to expand production capacity at their manufacturing facilities in Ipswich and Rowley, Massachusetts. NEB will utilize multiple customized stainless-steel fermenters for high-density Escherichia coli fermentation. Delivery of the ABEC 400 L and 1000 L fermenters is expected by mid-2021.
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11 月,ABEC 宣布,新英格兰生物实验室(NEB)选择 ABEC 来扩大其位于马萨诸塞州伊普斯威奇和罗利的制造工厂的生产能力。NEB 将使用多个定制的不锈钢发酵罐进行高密度大肠杆菌发酵。ABEC 400 升和 1000 升发酵罐预计将于 2021 年年中交付。
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ABEC announced in November that Qilu Pharmaceutical again selected ABEC to rapidly expand production capacity at Qilu's cGMP manufacturing facility in Jinan, Shandong, China. ABEC is delivering several sets of large-scale, stainless steel, cell culture bioreactors. ABEC's large-scale bioreactors previously installed at Qilu are currently the largest in operation in China.
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ABEC 在 11 月宣布,齐鲁制药再次选择 ABEC 来快速扩大其位于中国山东济南的齐鲁 cGMP 制造工厂的产能。ABEC 正在交付几套大型不锈钢细胞培养生物反应器。ABEC 以前安装在齐鲁的大型生物反应器目前是中国运行中最大的生物反应器。
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In October, Cytiva announced it will provide its FlexFactory to Akron Biotech, a provider of cGMP-compliant solutions to support advanced therapy development. FlexFactory is a flexible, single-use platform that will enable Akron Biotech to manufacture plasmid DNA. This will be the first Cytiva FlexFactory to be used in the manufacture of plasmid DNA. There are more than 70 FlexFactory installations worldwide.
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10 月,Cytiva 宣布将向符合 cGMP 标准的解决方案提供商阿克伦生物技术公司提供 FlexFactory,以支持高级疗法开发。FlexFactory 是一个灵活的一次性平台,它将使阿克伦生物技术能够制造质粒 DNA。这将是第一个用于制造质粒 DNA 的 Cytiva Factory。全球有 70 多个 FlexFactory 安装。
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In November, Cytiva announced it is installing its first FlexFactory in the Middle East and North African region as part of Saudi Vax's planned Saudi Vaccine and Bioprocessing Center (SVBC), a Saudi government-funded project led by King Abdulaziz City for Science and Technology and the National Industrial Development Center. The SVBC will use Cytiva's FlexFactory to manufacture halal vaccines and biologics in-region, for-region.
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11 月,Cytiva 宣布将在中东和北非地区安装首个 FlexFactory,作为沙特瓦克斯计划中的沙特疫苗和生物加工中心(SVBC)的一部分,该中心是由阿卜杜勒阿齐兹国王科学技术和国家工业城领导的沙特政府资助的项目开发中心。SVBC 将使用 Cytiva 的 FlexFactory 在区域内、区域内生产清真疫苗和生物制剂。
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In November, life science firm Cytiva announced it is supporting Clover Biopharmaceuticals, a global clinical-stage biotechnology company, to help accelerate the development and manufacturing of a protein-based S-Trimer subunit vaccine candidate. Clover aims to quickly expand its current 2 x 2000 L capacity of the Cytiva FlexFactory, which went into service in January. Cytiva will help Clover add two more 2000 L bioreactors for a total of 4 x 2000 L manufacturing capacity through the Cytiva FlexFactory.
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11 月,生命科学公司 Cytiva 宣布将支持全球临床阶段的生物技术公司三叶草生物制药公司,以帮助加快基于蛋白质的 S-Trimer 亚单位候选疫苗的开发和制造。三叶草的目标是快速扩大 Cytiva FlexFactory 目前的 2 x 2000 升容量,该工厂已于 1 月投入使用。Cytiva 将通过 Cytiva Factory 帮助三叶草再增加两台 2000 升生物反应器,总制造能力为 4 x 2000 升。
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Product Introductions
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产品介绍
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In October, Shimadzu introduced the TOC-1000e, the first analyzer in the eTOC Series of online TOC analyzers designed for pure-water applications. The TOC-1000e has the world's smallest and lightest cabinet, according to the company, with a detection limit of 0.1?g/L, making it ideal for fields requiring high-purity water, including pharmaceuticals, semiconductors, food & beverages, chemistry and precision equipment.
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10 月,岛津推出了 TOC-1000e,这是专为纯水应用而设计的 eOC 系列在线 TOC 分析仪中的第一台分析仪。根据该公司的说法,TOC-1000e 拥有世界上最小、最轻的机柜,检测限为 0.1?g/L,非常适合需要高纯度水的领域,包括药品、半导体、食品和饮料、化学和精密设备。
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Materials Characterization
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材料表征
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Company Announcements
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公司公告
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This summer, Element Materials Technology, a materials and product qualification testing firm, made a strategic investment in Plastometrex, a start-up developing technical and software-led solutions for testing in material science. Pastometrex is pioneering alternative techniques to conventional mechanical testing methods that utilize advanced numerical modelling, optimization algorithms and machine learning to accurately predict plasticity, residual stresses and creep parameters from indentation test data.
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今年夏天,材料和产品认证测试公司元素材料技术对 Plastometrex 进行了战略投资,该公司是一家开发以技术和软件为主导的材料科学测试解决方案的初创公司。Pastometrex 开创了传统机械测试方法的替代技术,这些方法利用先进的数值建模、优化算法和机器学习,从压痕测试数据中准确预测可塑性、残余应力和蠕变参数。
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In August, CANNON Instrument, whose products include viscometers, rheometers, flash point testers and physical property testing equipment, announced a 12,000 ft2 (1,115 m2) addition to its facility, expanding it to 50,000 ft2 (4,645 m2).
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8 月,CANON 仪器公司的产品包括粘度计、流变仪、闪点测试仪和物理性能测试设备,宣布增加 12,000 平方英尺(1,115 平方米)的设施,将其扩建至 50,000 平方英尺(4,645 平方米)。
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In October, Stanhope-Seta, a supplier of petroleum analyzers, announced that the Canadian General Standards Board confirmed the inclusion of ASTM D8073 (WSI) in mandatory Table 1 of the Canadian Jet fuel specification, CGSB 3.23-2019 of its Water Separation Instrument (WSI) SA-9000-0>.
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10 月,石油分析仪供应商 Stanhope-Seta 宣布,加拿大通用标准委员会确认将 ASTM D8073(WSI)纳入加拿大喷气燃料规范的强制性表 1,即 CGSB 3.23-2019 的水分离仪器(WSI)SA-9000-0>。
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In November, Halo Labs, a life science instrumentation company developing tools for biologics researchers, named Rick Gordon as CEO and Board member. He replaces Robert Wicke who resigned in October but remains on the Board. Mr. Gordon most recently served as the Vice President of Global Sales for Halo Labs.
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11 月,为生物制剂研究人员开发工具的生命科学仪器公司 Halo Labs 任命里克·戈登为首席执行官兼董事会成员。他取代了 10 月份辞职但仍在董事会成员的罗伯特·威克。戈登先生最近担任 Halo Labs 的全球销售副总裁。
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H.E.L Group, a developer and manufacturer of innovative laboratory tools for process optimization, safety and scale-up including the BTC 500 adiabatic calorimeter, announced in November full regulatory compliance for its battery testing protocols and equipment in China associated battery packs for electric vehicles, with a focus on mechanical, electrical and thermal stress.
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H.E.L 集团是一家用于过程优化、安全和放大生产的创新实验室工具的开发商和制造商,包括 BTC 500 绝热量热计,该集团于 11 月宣布其电池测试协议和中国相关电池组设备完全符合法规要求车辆,重点关注机械、电气和热应力。
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Product Introductions
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产品介绍
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In September, NanoTemper Technologies, which creates tools that address challenging characterizations, introduced the Prometheus Panta, a multi-parameter stability characterization instrument. It combines dynamic light scattering for particle size determination with nanoDSF (a label-free version of differential scanning fluorimetry), for thermal unfolding and back reflection for aggregation. Applications include biologics formulation optimization, developability or comparability assessments. According to the company, for the first time, researchers are able to correlate particle sizing, thermal unfolding and aggregation results collected throughout an entire thermal ramp.
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9 月,NanoTemper Technologies 推出了多参数稳定性表征仪器 Prometheus Panta,这是一款多参数稳定性表征仪器,该公司开发了解决具有挑战性的表征的工具它将用于测定粒径的动态光散射与 nanoDSF(差示扫描荧光法的无标签版本)相结合,用于热展开和反射以进行聚集。应用包括生物制剂配方优化、可开发性或可比性评估。据该公司称,研究人员首次能够关联整个热斜坡上收集的颗粒大小、热展开和聚集结果。
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In September, CANNON Instrument launched a new model to the CANNON TESC lineup, model TESC-5133. The compact, economical TESC-5133 (Thermoelectric Sample Conditioner System) integrates and automates the ASTM D5133 process of conditioning and testing low–temperature viscosities of engine lubricants. Incorporating a Brookfield DV2T digital viscometer, with an easy lift system to simplify positioning of the viscometer head, and a thermoelectrically controlled sample chamber, the TESC-5133 automates the entire conditioning and testing process, recording sample temperatures and viscosities throughout the test then computing the temperature (Gelation Index Temperature) at which there is a rapid change in viscosity (Gelation Index).
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9 月,CANNON 仪器推出了 CANNON TESC 阵容的新型号,型号为 TESC-5133。紧凑、经济的 TESC-5133(热电样品调理系统)集成并自动化了 ASTM D5133 调节和测试发动机润滑油低温粘度的过程。TESC-5133 结合了 Brookfield DV2T 数字粘度计、简化粘度计头定位的简易升降系统和热电控制的样品室,可自动执行整个调理和测试过程,记录整个测试过程中的样品温度和粘度然后计算粘度快速变化的温度(凝胶指数温度)(凝胶指数)。
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Setaram announced in September the THEMYS ONE is an accessible and versatile thermal analysis platform for temperature, mass variation, heat and heat flow, and evolved gas measurements. The THEMYS ONE+ version offers high throughput with its 32-position autosampler. It can reach temperatures as high as 1150 °C or 1600°C.
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Setaram 在 9 月宣布,THEMYS ONE 是一个可访问且多功能的热分析平台,用于温度、质量变化、热量和热流量以及演变气体测量。THEMYS ONE+ 版本凭借其 32 位自动进样器提供了高吞吐量。它的温度可以高达 1150 °C 或 1600°C。
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In October, Halo Labs introduced the Aura BMI, a non-fluorescence version of its Aura particle characterization platform. It adds improved optics for greater sensitivity, increased linear range and the option to upgrade to fluorescence particle identification for full Fluorescence Membrane Microscopy. The Aura BMI option delivers the ability to meet requirements of both low-volume and large-volume testing.
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10 月,Halo Labs 推出了 Aura BMI,这是其 Aura 粒子表征平台的非荧光版本。它增加了改进的光学元件,以提高灵敏度,增加线性范围,并可以选择升级为全荧光膜显微镜的荧光粒子识别。Aura BMI选项能够满足小批量和大批量测试的要求。
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In October, Buehler released its newest Rockwell Hardness Tester, the Wilson RH2150, an updated more advanced Rockwell tester with easy programmability, advanced calculations and even verification reminders to ensure compliance. The RH2150 is available in two different sizes, with a vertical capacity of 10 in and 14 in (254 mm and 356 mm), respectively.
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10月,Buehler发布了最新的洛氏硬度计Wilson RH2150,这是一款更先进的洛氏硬度测试仪,具有易于编程的功能、先进的计算功能,甚至还有验证提醒,以确保合规性。RH2150 有两种不同的尺寸可供选择,垂直容量分别为10英寸和14英寸(254毫米和356毫米)。
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